1220 Infinity LC System II
The Agilent 1220 Infinity II LC System is an affordable, high quality UHPLC system for routine standard analyses that maximizes uptime, minimizes maintenance and provides the highest return on your investment.
As a member of the 1200 Infinity II Series it gives you the proven quality and performance you expect from the industry leader, in your choice of four easy to own, integrated, "all-in-one" configurations.
The new 1220 Infinity II LC with integrated diode-array detector can also be used for mobile applications.
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Winner of the Scientists’ Choice Award as Best New Separations Product of 2010.
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Optimized for everyday productivity - exceptional accuracy and superior precision for all routine applications.
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Fully compliant with all requirements for regulatory LC applications.
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Industry leading quality and long-life - a member of the reliable and trusted 1200 Infinity Series.
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Fast, trouble-free startup - every system is tested in its final configuration.
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Flexibility - hardware choices and all-in-one configurations include an isocratic or gradient pump, manual injector or vial autosampler, column oven and variable wavelength detector.
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Future proof - upgrade your system with additional hardware modules such as a 1200 Infinity Series refractive index, fluorescence or evaporative light scattering detector, or a 6000 Series Single Quadrupole MS.
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Higher resolution and faster run times - our optimized pump delivers up to 600 bars so you can use smaller particle size columns.
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High pressure capabilities - get up to 600 bars from our integrated autosampler and manual injector.
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Lower detection limits using a variable wavelength detector up to 80 Hz.
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High performance software - chose either OpenLAB EZChrom Edition or the fully flexible, multi-purpose OpenLAB Chemstation Edition.
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Agilent 1220 Infinity II LC System - Performance Specifications |
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Safety features |
Extensive diagnostics, error detection and display, leak detection, safe leak handling, leak output signal for shutdown of pumping system. Low voltages in major maintenance areas. |
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Control and data evaluation |
Agilent EZChrom Compact, Agilent Lab Advisor, Agilent ChemStation, Agilent EZChrom Elite |
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Communications |
Controller-area network (CAN), RS-232C, APG Remote: ready, start, stop and shut-down signals, LAN |
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GLP features |
Early maintenance feedback (EMF), electronic records of maintenance and errors |
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Agilent 1220 Infinity II LC System – Performance Specifications Pumps (isocratic and gradient) |
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Hydraulic system |
Dual plunger in series pump with proprietary servo-controlled variable stroke drive, floating plungers and passive inlet valve |
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Settable flow range |
0.001 – 10 mL/min, in 0.001 mL/min increments |
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Flow range |
0.2 – 10.0 mL/min |
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Flow precision |
<0.07% RSD, or < 0.02 min SD whatever is greater, based on retention time at constant room temperature |
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Flow accuracy |
± 1% or 10 μl/min whatever is greater |
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Pressure |
Operating range 0 – 60 MPa (0 – 600 bar, 0 – 8700 psi) up to 5 mL/min |
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Pressure pulsation |
< 2 % amplitude (typically < 1 %), at 1 mL/min isopropanol, at all pressures > 1 MPa (10 bar) |
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Compressibility compensation |
User-selectable, based on mobile phase compressibility |
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Recommended pH range |
1.0 – 12.5, solvents with pH < 2.3 should not contain acids which attack stainless steel |
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Gradient formation (gradient pump or optional; two solvents) |
Low pressure dual mixing/gradient capability using proprietary high-speed proportioning valve |
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Composition range |
0 – 95 % or 5 – 100 %, user selectable |
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Composition precision |
< 0.2 % RSD or < 0.04 min SD, whatever is greater, at 1 mL/min; based on retention time at constant room temperature |
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Agilent 1220 Infinity II LC System Performance Specifications – Integrated degassing unit (gradient pump only) |
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Maximum flow rate |
10 mL/min per channel |
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Number of channels |
2 |
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Internal volume |
1.5 mL/channel |
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Agilent 1220 Infinity LC System - Performance Specifications Autosampler |
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Pressure |
Operating range 0 – 60 MPa (0 – 600 bar, 0 – 8700 psi) |
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Injection range |
0.1 – 100 μL in 0.1 μL increments |
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Replicate injections |
1 – 99 from one vial |
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Precision |
< 0.25% RSD from 5 – 100 μL, < 1% RSD 1 – 5 μL variable volume |
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Minimum sample volume |
1 μL from 5 μL sample in 100 μL microvial, or 1 μL from 10 μL sample in 300 μL microvial |
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Carryover |
Typically < 0.1%, < 0.05% with external needle cleaning |
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Sample viscosity range |
0.2 – 50 cp |
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Sample capacity |
100 × 2-mL vials in 1 tray |
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Injection cycle time |
Typically 50 s depending on draw speed and injection volume |
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Agilent 1220 Infinity LC System - Performance Specifications Oven |
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Temperature range |
5°C above ambient to 80°C |
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Temperature stability |
± 0.15°C |
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Temperature accuracy |
± 0.8°C with calibration ± 0.5°C |
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Column capacity |
One 25-cm column |
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Internal volume |
6 μL |
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Agilent 1220 Infinity II LC System Performance Specifications Variable Wavelength Detector |
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Detection type |
Double-beam photometer |
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Light source |
Deuterium lamp |
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Wavelength range |
190 – 600 nm |
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Short term noise |
± 0.35 × 10-5 AU, at 230 nm |
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Drift |
3 × 10-4 AU/hr, at 254 nm |
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Linearity |
> 2 AU (5%) upper limit |
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Wavelength accuracy |
± 1 nm; Self-calibration with deuterium lines, verification with holmium oxide filter |
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Band width |
6.5 nm typical |
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Flow cells |
Standard: 14- μL volume, 10-mm cell path length and 40 bar (588 psi) pressure maximum |
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Agilent 1220 Infinity II LC System Performance Specifications Diode Array Detector (G4294B only) |
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Detector type |
1024-element diode array |
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Light source |
Deuterium and tungsten |
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Number of signals |
8 |
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Maximum sampling rate |
80 Hz |
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Short-term noise |
< ± 0.7 x 10-5 AU at 254/4 nm and at 750 nm, TC 2 s |
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Drift |
< 0.9 x 10-3 AU/hr at 254 nm |
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Linearity |
> 2.0 AU (5 %) at 265 nm |
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Wavelength range |
190-950 nm |
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Wavelength accuracy |
± 1 nm, self-calibration with deuterium lines verification with holmium oxide filter |
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Slit width |
Programmable: 1, 2, 4, 8, 16 nm |
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Diode width |
< 1 nm |
