Benzodiazepines in Plasma / Serum

Benzodiazepines (BZP) are a group of psychoactive drugs with a broad range of therapeutic effects. They belong to the most frequently prescribed drugs all over the world.

Manual Sample Preparation.

The ClinMass® Add-on Set for Benzodiazepines (order no. MS9500) contains all analyte specific components required for the quantification of 36 different drugs and metabolites. The ClinMass® TDM Platform (order no. MS9000) contains the components needed for sample preparation and LC-MS/MS analysis. It can be used with all ClinMass® Add-on Sets of the TDM Kit System (BZP, TCA, …). The analytical column is suitable for the whole analyte panel (156 compounds).

On-line SPE

The ClinMass® Add-on Set for Benzodiazepines (order no. MS9550) contains all analyte specific components required for the quantification of 35 different drugs and metabolites. The ClinMass® TDM Platform (order no. MS9050) contains the components needed for on-line SPE LCMS/MS analysis. It can be used with all ClinMass® Add-on Sets of the “TDM Kit System, on-line”. The analytical column is suitable for the whole analyte panel (153 compounds).

Analytical Parameters: 

7Aminotritazepam Zalepion Norclobazam Desalkylflurazeram Trazadone
7aminociotrazepam  OH-Triazolam Lorazepam Flunitrazepam Flurazepam
3Hydroxibromazepam OH-Alprazolam Clonazepam Temazepam Midazolam
7Aminoflunitrazepam Desmethylunitrazepam Zolpidem Chlordiazepoxide Brotizolam Diazepam
Bromazepam Oxazepam Alprazolam Nordiazepam Tetrazepam
Demoxepam Nitrazepam OH-Midazolam Clobazam Prazepam
Zopiclon Estarblam Trizaolam    Lometazepan Medazepam

 

We have available an user manual for this application. You can request sending an email to clinica@ingenieria-analitica.com