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Antiepileptic Drugs in Plasma / Serum

Antiepileptic drugs (AED) are used for the treatment of epilepsy, a chronic neurological disorder, which is characterised by recurrent epileptic seizures.

Manual Sample Preparation

The ClinMass® Add-on Set for Antiepileptic Drugs (order no. MS9200) contains all analyte specific components required for the quantification of 27 different AEDs and metabolites. The ClinMass® TDM Platform (order no. MS9000) contains the components needed for sample preparation and LC-MS/MS analysis. It can be used with all ClinMass® Add-on Sets of the TDM Kit System. The analytical column is suitable for the whole analyte panel (156 compounds).

On-line SPE

The ClinMass® Add-on Set for Antiepileptic Drugs (order no. MS9250) contains all analyte specific components required for the quantification of 26 different AEDs and metabolites. The ClinMass® TDM Platform (order no. MS9050) contains the components needed for on-line SPE LCMS/MS analysis. It can be used with all ClinMass® Add-on Sets of the “TDM Kit System, on-line” (BZP, TCA, …). The analytical column is suitable for the whole analyte panel (153 compounds).

Analytical Parameters: 

10-OH Cabamazepine Levetiracetam Retigabine
Carbamazepine N-Desmethylmethsuximide Rufinamide
Carbamazepine-diol Oxcarbazepine Stiripentol
Carbamazepine-epoxide PEMA Sulthiame
Felbamate Perampanel Tiagabine
Ethosuximide Phenorbarbital Topiramate
Gabapentine Phenytoin Valproic Acid
Lacosamide Pregabaline Zonisamide
Lamotrigine Primidone  

 

We have available an user manual for this application. You can request sending an email to clinica@ingenieria-analitica.com