[¹⁸F]FDG is a radioactive glucose molecule used for PET imaging. It produces images that show the metabolic activity of tissues. In FDG-PET scanning, the high consumption of the sugar by tumor cells, as compared to the lower consumption by normal surrounding tissues, identifies these cells as cancer cells.
The ALEXYS analyzer for FDG provides a reliable solution for the quality control of FDG as required by the US and European Pharmacopeia (USP and EP). The DECADE Elite electrochemical detector in combination with a CarboPac column allows fast analysis of 8 minutes. The EP and USP methods are both evaluated and in compliance.
- In compliance with EP & USP
- Reproducible & robust
- Fast
- Longer lifetime of gold electrode
System Configuration
For the analysis of FDG we selected the Flexcell electrochemical cell. This cell has an exchangeable working electrode which is particularly useful in pulsed electrochemical detection. The electrode material tends to vanish over the years, in the process. Exchanging an electrode disc only takes a few minutes. The HyREF is maintenance free even at pH 13! The ALEXYS Analyzer (180.0053E) comprises the following parts:
- Injection valve (AS 110 autosampler is optional)
- LC 110S HPLC pump
- OR 110 organiser
- Clarity data acquisition software
- DECADE Elite electrochemical detector
- Flexcell with Au WE, HyREF
- HPLC column with pre-column
- ALEXYS LC connection kit
- Polyethylene bottle kit
