1260 Infinity Bio-Inert Quaternary LC System
The Agilent 1260 Infinity Bio-inert Quaternary LC System is a dedicated solution for large bio-molecule analysis. The design of new metal-free components in the sample flow-path and the absence of iron and steel in solvent delivery ensures the integrity of bio-molecules, minimizes unwanted surface interactions and increases column life-time. This is ideal when working under harsh solvent or extreme pH conditions. The power range expands from lowest pressure for traditional bio-purification columns up to high pressure STM analytical bio-columns. Together with the Agilent Bio-HPLC column portfolio for SEC and IEX, highest resolution per time is achieved for protein and NBE characterization. Enable advanced SEC of large biomolecules with the new Agilent 1260 Infinity Multi-Detector Bio-SEC columns.
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Advanced characterization of bio-therapeutics
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Complete metal-free sample contacting surfaces throughout the system.
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Mobile phase wetted parts are iron and steel free in solvent delivery unit.
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Low and high-pressure column capability (0 - 600 bar) and 10x higher analysis sensitivity.
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High salt tolerance (2M) and wide pH range (1-13, short term 14) for increased flexibility.
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Active seal wash and quaternary solvent blending included.
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Analytical and semi-prep up to 10 mL/min with inert fraction collection.
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Inert flow-cells for UV and fluorescence detection and inert solvent and column selection valves.
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Novel capillary and connection design
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Large portfolio of Bio-HPLC columns for SEC, IEX, reversed phase and peptide mapping
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High efficiency Bio-SEC columns providing maximum resolution
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Upgrade to advanced Bio-SEC
Agilent 1260 Infinity Bio-inert Quaternary Pump (G5611A)
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Type |
Specifications |
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Hydraulic system |
Dual plunger in series pump with proprietary servo-controlled variable stroke drive, floating plungers and active inlet valve, integrated 4-channel degassing unit |
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Setable flow range |
0.001 – 10 mL/min, in 0.001 mL/min increments |
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Recommended flow range |
0.2 – 10.0 mL/min |
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Flow precision |
< 0.07% RSD, or < 0.02 min SD whatever is greater, based on retention time at constant room temperature |
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Flow accuracy |
± 1% or 10 μL/min whatever is greater |
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Pressure |
Operating range 0 – 60 MPa (0 – 600 bar, 0 – 8700 psi) up to 5 mL/min |
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Pressure pulsation |
< 2 % amplitude (typically < 1.3 %), at 1 mL/min isopropanol, at all pressures > 1 MPa (10 bar) |
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Compressibility compensation |
User-selectable, based on mobile phase compressibility |
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Recommended pH range |
1.0 – 13, short term 14 |
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Gradient formation |
Low pressure quaternary mixing/gradient capability using proprietary high-speed proportioning valve |
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Composition range |
0 – 95% or 5 – 100%, user selectable |
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Composition precision |
< 0.2% RSD, at 0.2 and 1 mL/min |
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Control and data evaluation |
Agilent control software (e.g. ChemStation, EZChrom, OL.) |
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Communications |
Controller-area network (CAN), GPIB, RS-232C, APG Remote: ready, start, stop and shut-down signals, LAN optional |
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Wetted materials |
Titanium, Gold, Platin-Iridium, Sapphire, PEEK, PEKK, PTFE |
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Active seal wash |
Included |
