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1290 Infinity Binary LC System

The Agilent 1290 Infinity Binary LC is not only the most powerful but also the most adaptive UHPLC system available. No matter what your laboratory requires, the 1290 Infinity Binary LC can handle the widest range of applications; UHPLC methods, legacy HPLC methods, HPLC-to-UHPLC method transfer, method development, multi-compound screening, LC/MS coupling, and many more.

  • Most adaptive  – emulates other HPLC and UPLC systems, connects to all Agilent and many non-Agilent software
  • Highest performance & flexibility – by any measure
  • HPLC-like service costs – UHPLC productivity

  • Intelligent System Emulation Technology (ISET) provides seamless transfer of methods between LCs, regardless of the brand, delivering unchanged retention time and peak resolution.

  • Infinite power range that combines ultra high pressure up to 1200 bar and high flow rates up to 5 mL/min for maximum chromatographic performance, compatibility, flexibility and investment protection.

  • The 1290 Infinity binary pump combines active damping with lowest delay volume down to <10 µL

  • Optical design in 1290 Diode Arrray Detector – including Agilent Max-Light cartridge flow cell – offers a new level of UV-sensitivity and baseline robustness, including fast spectral acquisition at data rates up to 160 Hz.

  • Ultra sensitivity is achieved through revolutionary Agilent Max-Light cartridge cell with 60 mm optical path length (typical noise: < ± 0.6 µAU/cm) providing more than 10 times higher sensitivity than the 1200 Series DAD and VWD.

  • Expand your UV-detection capabilities with the 30x wider linear UV-range offered by the new HDR-DAD solution - making it ideal for analysis of mixtures with widely different concentration levels.

  • Next generation flow-through design of the 1290 Infinity Autosampler achieves lowest carry over (<0.004%)

  • 1290 Infinity Flexible Cube combined with the 1290 Infinity Autosampler to facilitate automatic backflushing of needle seat for a new benchmark in lowest carry over (typically <0.0010%, <10 ppm)

  • 1290 Infinity LC injector HTC/HTS is designed specifically to meet the throughput and reliability demands of critical LC/MS applications, offering lowest carryover with dynamic load and wash (DLW) principle.

  • Pull-out valve drive and user-exchangeable valve heads in the 1290 Infinity Thermostatted Column Compartment boosts usability and paves the way for ultra high-throughput, multi-method and automated method development solutions.

  • ZORBAX Rapid Resolution High Definition (1.8 µm) LC columns facilitate easy, fast and secure method transfer from HPLC to UHPLC through identical column chemistries.

  • Lab Advisor Software– with intuitive diagnostic and monitor capabilities and alert functions to notify you of problems – helps you manage your lab for best chromatographic quality

Analysis of DNPH-derivatized Aldehydes and Ketones using the Agilent 1220 Infinity LC System with Diode Array Detector.pdf Analysis of 2,4-D, 2,4,5-T, Bromoxynil, and Dinoseb Herbicides in DW by 6495 LC-MS-MS.pdf Adapting EPA Method 8330B for Analysis of Explosives in Water to SPE and LC-MS-MS.pdf Analysis of PAHs in soil according to EPA 8310 method with UV and fluorescence detection.pdf EPA Method 509.1 Using the 290 Infinity UHPLC and a 6460 Triple Quadrupole LC-MS.pdf Direct Aqueous Analysis of Pharmaceuticals in Water at ppt Levels by LC-MS-MS with the Agilent 6490 Triple Quadrupole LC-MS System with Ion Funnel Technology.pdf Automated alternating column regeneration on the Agilent 1290 Infinity LC.pdf Fast LC-MS-MS Analysis of Group 4 Pharmaceuticals from EPA-1694 with RRHD HILIC Plus.pdf EPA Method 538. Determination of Selected Organic Contaminants in Drinking Water by Direct Aqueous Injection with the Agilent 6460 Triple Quadrupole LC-MS System.pdf Fast analysis of polyaromatic hydrocarbons using the Agilent 1290 Infinity LC and Eclipse PAH columns.pdf High Resolution Mass Spectrometry (LC-Q-TOF-MS) for the Detection of Pharmaceuticals in Water.pdf High Throughput Method Development for PAHs using the Agilent 1290 Infinity LC system and a ZORBAX Eclipse PAH column.pdf High Sensitivity HPLC Analysis of Perchlorate in Tap Water Using an Agilent 6460 Triple Quadrupole LC-MS System.pdf High-throughput method development for aldehydes and ketones using an Agilent 1290 Infinity LC System and an Agilent ZORBAX StableBond HD column.pdf On-line SPE Enrichment of Trace Organic Contaminants in Water and Juices.pdf Identification of Unknown Microcystins in Alberta Lake Water.pdf Pesticide Analysis using an Agilent 1290 Infinity LC System with an Agilent 6140 Single Quadrupole LC-MS System.pdf Rapid Method Development for 18 PAH Compounds with an Agilent RRHD Eclipse PAH Column.pdf Sensitive LC-MS Quantitation of Trace Organic Contaminants in Water with Online SPE Enrichment.pdf Screening and identification of marine biotoxins.pdf Solid Phase Extraction of Organophosphorus Pesticides in Water with Agilent Bond Elut PPL.pdf Screening for Emerging Chemical Contaminants in Water Using LC-QTOF and Mass Profiler Professional Software.pdf Trace analysis of explosives in soil samples using the Agilent 1290 Infinity LC System equipped with an Agilent Max-Light 60-mm cartridge cell.pdf

Screening and Verifying Mycotoxins in Food.pdf High Throughput Method Development for PAHs using the Agilent 1290 Infinity LC System and a ZORBAX Eclipse PAH Column.pdf Analysis of color additives in sweets.pdf Analysis of water-soluble vitamins from multivitamin tablets for nutrition labeling.pdf HPLC Analysis with Fluorescence Detection of Chlorophyll Degradation Products Pheophytins and Pyropheophytin in Virgin Olive Oil.pdf Determination of Pesticide Multiresidues in Apple, Pear and Grape using modified QuEChERS and analysis by LC-QTOF MS.pdf Analysis of foods using HPLC with evaporative light scattering detection.pdf Agilent 1290 Infinity Binary LC System with ISET - Emulation of the Waters Alliance 2695 LC system analyzing antioxidants.pdf Agilent 1290 Infinity Binary LC with ISET – emulation of the Waters Alliance 2695 LC system analyzing aromatic acids.pdf 2-Dimensional separation of polyphenols in beverages using the Agilent 1290 Infinity 2D-LC Solution and software-assisted 2D-LC data analysis for comparison of ingredients.pdf Analysis of Anthocyanins in Common Foods Using an Agilent Poroshell 120 SB-C18.pdf Analysis of Low-Calorie Sweeteners by Liquid Chromatography-Tandem Mass Spectrometry.pdf Analysis of ascorbic acid, citric acid and benzoic acid in orange juice.pdf Assessment of Bisphenol A Specific Migration from Packaging Materials into Food Simulants Using UHPLC-MS-MS and LC with Fluorescence Detection.pdf Application of a Triggered MRM Database and Library for the Quantitation and Identification of Pesticides in Food Extracts.pdf Automatic Precolumn Derivatization of Amino Acids and Analysis by Fast LC using the Agilent 1290 Infinity LC System.pdf Both High-Resolution Chromatography and Accurate Mass Spectrometry are Essential for Analysis of Isobaric Pesticides in Complex Food Matrices.pdf Characterization of Red Yeast Rice Products and Raw Materials.pdf Characterization of Steroidal Saponins From Two Dioscorea Species Using Liquid Chromatography and the Agilent 6500 Series Accurate-Mass Q-TOF LC-MS.pdf Determination of Hormones in Shrimp by Agilent 1290 Infinity LC with Agilent Poroshell 120 LC Column and Agilent QuEChERS for Sample Preparation.pdf Detection of Aflatoxigenic Fungi and Toxins from Export Grade Peanut Samples. Comparison of qPCR and LC-MS Techniques.pdf Determination of Melamine and Its Analogues from Powdered Infant Milk Using Polymeric Solid Phase Extraction.pdf Determination of pesticides in baby food by UHPLC-MS-MS using the Agilent 1290 Infinity LC system and the Agilent 6460 triple quadrupole LC-MS.pdf Development of an Analytical Method for Determination of Antiparasitics Residues in Milk Using QuEChERS and Analysis by LC-MS-MS.pdf Fast Analysis of Eleutherosides in Siberian Ginseng Using the Agilent 1290 Infinity LC and Eclipse 1.8 μm Column.pdf Fast analysis of resveratrol in red wine using the Agilent 1290 Infinity LC System.pdf Development and Application of an Exact Mass LC-MS-MS Library for the Accurate Mass Screening and Quantitation of Pesticides in Fruits and Vegetables.pdf Fast Analysis of Terpene Lactones in Ginkgo Biloba Extract Using the Agilent 1290 Infinity LC and Agilent Poroshell 120 SB-C18 2.7 μm Column.pdf Fast Analysis of Silymarins in Milk Thistle Using the Agilent 1290 Infinity LC System and an Agilent ZORBAX Eclipse Plus C18 1.8 μm Column.pdf Fast Analysis of Triterpene Glycosides in Black Cohosh Using the Agilent 1290 Infinity LC System and an Agilent Poroshell 120 SB C-18 2.7 μm Column.pdf Fast and Quick Detection of Melamine and Its Analogues from Powdered Infant Milk.pdf FOOD CAMPAIGN 2012.pdf High resolution of complex lipids (triglycerides) using the Agilent 1290 Infinity LC and ZORBAX RRHT and RRHD 1.8 μm columns.pdf Fast Separation of Food Preservatives Using an Agilent Poroshell 120 EC-C18 Column.pdf High-Resolution Analysis of Intact Triglycerides by Reversed Phase HPLC Using the Agilent 1290 Infinity LC UHPLC System.pdf Modified QuEChERS for HILIC LC-MS-MS Analysis of Nicotine and Its Metabolites in Fish.pdf Maximizing efficiency using Agilent Poroshell 120 columns.pdf Identification of Imidacloprid Metabolites in Onions Using High Resolution Accurate Mass Spectrometry (LC-Q-TOF MS) and Accurate Mass Tools.pdf Multi-Residue Pesticide Screening and Quantitation in Difficult Food Matrixes Using the Agilent 6495 Triple Quadrupole Mass Spectrometer.pdf Online sample cleanup on the Agilent 1290 Infinity LC using a built in 2-position-6-port valve.pdf Optimizing Sample Preparation for LC-MS-MS of Pesticide Residues in Herbal Teas.pdf On-line SPE Enrichment of Trace Organic Contaminants in Water and Juices.pdf Profiling capsaicinoids in spicy foods and food products using Agilent 1290 Infinity LC and Agilent ZORBAX Poroshell 120 2.7 μm columns with UV-Vis diode.pdf Profiling medications for decorative or aquarium fish using the Agilent 1290 Infinity LC system and Agilent ZORBAX Poroshell 120 2.7 μm columns.pdf Quick, Easy and Reliable Detection of Histamine in Food Using the Agilent 6490 Triple Quadrupole LC-MS with Jet Stream Technology.pdf Rapid and Sensitive Detection of Ergot Alkaloids in Wheat Using the Agilent 6460 Triple Quadrupole LC-MS with Jet Stream Technology.pdf Rapid Gradient and Elevated Temperature UHPLC of Flavonoids in Citrus Fruit.pdf Sample Prep for Trace Analysis of Adulterants in Erectile Dysfunction Dietary Supplements.pdf Rapid, Sensitive and Cost-effective Detection of B Vitamins in Foods by UHPLC-MS-MS.pdf Speciation of Inorganic Arsenic in Baby Rice Cereals Using HPLC-ICP-MS.pdf Selectivity Comparison of Poroshell 120 Phases in the Separation of Butter Antioxidants.pdf UHPLC-MS Profiling of Nonvolatiles in Whiskeys Using the Agilent 6530 Accurate-Mass Q-TOF LC-MS and Mass Profiler Professional.pdf UHPLC-ESI Accurate-Mass Q-TOF MS-MS Approaches for Characterizing the Metabolism and Bioavailability of Quercetin in Humans.pdf Ultrafast analysis of synthetic antioxidants in vegetable oils using the Agilent 1290 Infinity LC system.pdf Ultrafast and sensitive analysis of sweeteners, preservatives and flavorants in nonalcoholic beverages using the Agilent 1290 Infinity LC system.pdf Use of High Resolution “All Ions MS-MS” Mass Spectrometry for Rapid Pesticide Confirmatory Screening.pdf

Transfer the EPUSP Method for Atorvastatin from a Traditional 5 µm Column to Poroshell 120.pdf Automated Sample Preparation by Protein Precipitation for High Throughput Bioanalysis.pdf High Resolution Glycopeptide Mapping of EPO Using an Agilent AdvanceBio Peptide Mapping Column.pdf Increased peak capacity for peptide analysis with the Agilent 1290 Infinity LC System.pdf Ultra High Speed and High Resolution Separations of Reduced and Intact Monoclonal Antibodies with Agilent ZORBAX RRHD Sub-2 μm 300 Diphenyl UHPLC Column.pdf QA-QC of monoclonal antibodies. High-resolution peptide mapping using the Agilent 1260 Infinity Bio-inert Quaternary LC and Agilent 1290 Infinity LC Systems.pdf A Generic UHPLC_UV_MS Method for Cleaning Verification of Highly Potent Drugs.pdf Maximizing chromatographic peak capacity with Agilent 1290 Infinity LC system by using gradient parameters.pdf Maximizing chromatographic peak capacity with the Agilent 1290 Infinity LC system.pdf A High Sensitivity Method for the Quantification of Fluvastatin in Plasma Using an Agilent 1290 Infinity Binary LC and an Agilent 6490 Triple Quadrupole Mass Spectrometer.pdf A UHPLC method to improve peak capacity of peptide mapping of digestion of factor IX.pdf Agilent 1290 Infinity Binary LC System with ISET - Emulation of the Waters Alliance 2695 LC system analyzing beta-blockers.pdf Agilent 1290 Infinity Binary LC System with ISET - Emulation of the Waters Alliance 2695 LC system analyzing endocrine disruptors.pdf Agilent 1290 Infinity LC the ideal partner for MS – Part 3 - Complimentary sensitivity of UV and MS detection.pdf Agilent 1290 Infinity Binary LC with ISET – Emulation of the Waters Alliance 2695 LC System Analyzing Analgesics.pdf Agilent 1290 Infinity LC The ideal partner for MS – Part 4.pdf Agilent 1290 Infinity LC The ideal partner for MS – Part 5.pdf Agilent 1290 Infinity LC The ideal partner for MS. Part 1 - Influence of delay volume and system dispersion on resolution and sensitivity.pdf Agilent 1290 Infinity LC with Agilent Poroshell columns for simultaneous determination of eight organic UV filters in under two minutes.pdf Analysis of Monoclonal Antibody (mAb) Using Agilent 1290 Infinity LC System Coupled to Agilent 6530 Accurate-Mass Quadrupole Time-of-Flight (Q-TOF).pdf Analysis of Pharmaceutical Substances Using HPLC and UHPLC Methods.pdf Analysis of Potential Genotoxic Arylamine and Aminopyridine Impurities in Active Pharmaceutical Ingredients.pdf Analytical instrument qualification and system validation according to USP Chapter (1058) for the Agilent 1290 Infinity LC system.pdf Determination of 32 Cathinone Derivatives and other Designer Drugs in Serum by Comprehensive LC-Triple Quadrupole-MS-MS Analysis.pdf Developing faster methods for generic drugs within EP 2.2.46E allowed limits.pdf Developing faster methods for generic drugs within USP (621) allowed limits.pdf Effective use of pharmacopeia guidelines to reduce cost of chromatographic analysis.pdf Extended ionization capability of Thermal Gradient Focusing ESI in High-Throughput in-vitro ADME assays.pdf Enhancing the Productivity of Pharmaceutical Workflows Using the Agilent 6150 Single Quadrupole Mass Spectrometer.pdf Fast impurity profiling of synthetic oligonucleotides with the Agilent 1290 Infinity LC System and Agilent 6530 Accurate-Mass QTOF LC-MS.pdf Fast screening of mobile and stationary phases with the Agilent 1290 Infinity LC and seamless method transfer to an Agilent 1200 Series LC using ISET.pdf High speed separation of anesthetics on the Agilent 1290 Infinity LC system with different columns.pdf High-throughput bioanalytical method development using UHPLC-triple quadrupole mass spectrometry.pdf High-Throughput LC-MS-MS for cytostatic drugs with an Agilent 1290 Infinity LC System coupled to a tandem mass spectrometer.pdf Increasing productivity in the analysis of impurities in metoclopramide hydrochloride formulations using the Agilent 1290 Infinity LC system.pdf Modernizing the USP Monograph for Impurity Profiling of Metoprolol Tartrate.pdf Quantification of alprazolam in dried blood spots using the Agilent 1290 Infinity LC System and Agilent 6460 Triple Quadrupole LC-MS System.pdf N-Glycan Profi ling Analysis of a Monoclonal Antibody Using UHPLC-FLD-Q-TOF.pdf Quantitation of Cystine and Identification of Related Metabolites in White Blood Cells Using a High Resolution Accurate Mass LC-MS Approach.pdf Reducing analysis time and solvent consumption for isocratic USP assay methods with current and proposed USP guidelines using the Agilent 1290 Infinity LC System.pdf Reducing total analysis cost for generic drugs within USP (621) allowed limits.pdf Sensitive Detection of Three Forms of Thyroid Hormone in Human Serum Using the Agilent 6490 Triple Quadrupole LC-MS System.pdf Scalability of Agilent Columns Across HPLC and UHPLC Instruments.pdf Several ZORBAX RRHD 1.8 μm Selectivities Facilitate Method Development.pdf Sensitivity enhancement for potential genotoxic impurity determination using the Agilent 1290 Infinity LC System and a 60 mm Agilent Max-Light Cartridge Cell.pdf Speed up the LC Analysis of Notoginsenoside R1 and Ginsenosides Rg1, Re, and Rb1 in Compound TCM Us Agilent 1290 Infinity LC and ZORBAX RRHD 1.8 μm.pdf Software-assisted, high-throughput identification of main metabolites of pharmaceutical drugs.pdf UHPLC method analysis of huang qin extract for injection and method transfer to HPLC.pdf Tryptic digest analysis using the Agilent 1290 Infinity LC System.pdf Analysis of pharmaceuticals and drug related impurities using Agilent instrumentation.pdf