Atypical Neuroleptics In Plasma / Serum
The drugs olanzapine, clozapine, quetiapine, risperidone, and paliperidone (= 9-OH-risperidone) belong to the class of the so called ”atypical” neuroleptics and are used for the treatment of schizophrenia. Co-medication, smoking, caffeine and food are factors that extensively influence their metabolism and thus lead to a high intra- and interindividual variability of drug concentrations in blood. In order to avoid severe side effects by overdosing and to ensure an optimal therapeutic effect, therapeutic drug monitoring (TDM) is required.
The RECIPE Complete Kit represents a fully automated, robust on-line SPE technique, which allows a direct sample injection into the HPLC system.
|
Order No. |
Description |
Quantity |
|
40000 |
ClinRep® Complete Kit for Atypical Neuroleptics in Plasma / Serum for 100 assays |
1 pce. |
|
Kit Components (order no. 40000): |
||
|
40009 |
SPE-Buffer |
2 x 40009 (2 x 1000 ml) |
|
40010 |
Mobile Phase |
2 x 40010 (2 x 2000 ml) |
|
40013 |
Plasma Calibrator, lyophil. |
5 x 3 ml |
|
Manual |
1 pce. |
|
|
Quick Reference |
1 pce. |
|
|
Optional Components: |
||
|
40012 |
Internal Standard IS |
2 ml |
|
40014 |
Test Solution, lyophil. |
5 x 2 ml |
|
40113 |
Plasma Calibrator, lyophil., for Risperidone and Paliperidone |
5 x 5 ml |
|
40114 |
Test Solution, for Risperidone and Paliperidone |
15 ml |
|
Start Accessories: |
||
|
40030 |
Analytical Column with test chromatogram |
1 pce. |
|
40031 |
SPE-Column |
1 pce. |
|
40032 |
Guard Column Holder incl. 1 Guard Column |
1 pce. |
|
40033 |
Guard Column |
5 pcs. |
|
FK7400 |
Inline-Filter (stainless steel sieve, free of dead volume) |
1 pce. |
|
Refill Service: |
||
|
40034 |
SPE-Column, refill (original column needs to be returned) |
1 pce. |
|
Accessories: |
||
|
FK1102 |
Switching valve, Sykam (6-port/3-channel) incl. electr. drive, PEEK |
1 pce. |
|
FK7340 |
Sealings and sieves |
4 pcs. each |
|
ClinChek® Controls: |
||
|
40080 |
Plasma Control, lyophil., Level I |
10 x 3 ml |
|
40081 |
Plasma Control, lyophil., Level II |
10 x 3 ml |
|
40082 |
Plasma Control, lyophil., Level I, II |
2 x 5 x 3 ml |
|
40180 |
Plasma Control, lyophil., for Risperidone and Paliperidone, Level I |
10 x 5 ml |
|
40181 |
Plasma Control, lyophil., for Risperidone and Paliperidone, Level II |
10 x 5 ml |
|
40182 |
Plasma Control, lyophil., for Risperidone and Paliperidone, Level I, II |
2 x 5 x 5 ml |
