1260 Infinity Binary LC System

The 1260 Infinity Binary LC system costs no more than a typical HPLC system, but yields faster results with significantly higher data quality. Delivering a pressure of 600 bars, this system boasts flat baselines and impressive sensitivity for diode array detector analyses thanks to the superior gradient accuracy from high pressure mixing. Based on the highly successful 1200 Series Rapid Resolution LC System, we promise full backwards compatibility for your established HPLC and RRLC methods. The binary system supports a wide range of LC and LC/MS applications with any narrow and standard bore analytical column.

  • Faster separations, higher resolution - the maximum 600 bar pressure system allows you to use smaller particle size columns.

  • Ultra-sensitivity through the revolutionary Agilent Max-Light cartridge flow cell with 60 mm optical path length (typical noise: < ± 0.6 µAU/cm).

  • Expand your UV-detection capabilities with the 30x wider linear UV-range offered by the new HDR-DAD solution  - making it ideal for analysis of mixtures with widely different concentration levels.

  • Baseline robustness and fast spectral acquisition at data rates up to 80 Hz through the new optical design of the 1260 Infinity Diode array Detector. Expand your UV-detection capabilities with the 30x wider linear UV-range offered by the new

  • HDR-DAD solution - making it ideal for analysis of mixtures with widely different concentration levels

  • Universal applicability - the configurable pump delay volume goes down to 120 μl, while the flow range can reach 5 ml/min at 600 bar so you can use columns ranging from narrow bore (2.1 mm ID) to standard bore (4.6 mm ID), matching the needs for both LC and LC/MS.

  • Large and small injection volumes - the next generation flow-through design of the 1260 Infinity Autosampler achieves highest precision for a wide range of injection volumes without changing sample loops.

  • High throughput and reliability, low carryover - the new 1290 Infinity LC Injector HTC/HTS  is designed specifically to meet the throughput and reliability demands of critical LC/MS applications, offering lowest carryover with dynamic load and wash (DLW) principle.

  • Flexibility and ultra-high throughput capabilities - new pull-out valve drive design and user-exchangeable QuickChange valve heads in the 1290 Infinity Thermostatted Column Compartment boosts usability and paves the way for ultra high-throughput, multi-method and automated method development solutions.

  • Easy method transfer - choose from a broad range of more than 140 Rapid Resolution High Definition  (1.8 µm) LC columns for easy, fast and secure method transfer from HPLC to UHPLC through identical column chemistries.

  • Intuitive, powerful software - new Lab Advisor software has diagnostic and monitoring capabilities and alert functions that warn you of problems so you can manage your lab and achieve the best chromatographic quality.

Specifications Agilent 1260 Infinity Binary Pump (G1312B) and VL version (G1312C)
Hydraulic system Two dual piston in series pumps with servo-controlled variable stroke drive, floating pistons
Settable flow range Set points 0.001 - 5 mL/min, in 0.001 mL/min increments
Flow range 0.05 - 5.0 mL/min
Flow precision ≤ 0.07% RSD or ≤ 0.02 min SD, whatever is greater; based on retention time at constant room temperature
Flow accuracy ± 1 % or 10 µL/min, whatever is greater; pumping degassed H2O at 10 MPa
(100 bar)
Pressure operating range 1260 Infinity Binary Pump:
Operating range up to 60 MPa (600 bar, 8700 psi) up to 5 mL/min

1260 Infinity Binary Pump VL:
Operating range up to 40 MPa (400 bar, 5880 psi) up to 5 mL/min
Pressure pulsation 1260 Infinity Binary Pump:
< 2 % amplitude (typically < 1.3 %) or < 0.3 MPa (3 bar), whatever is greater, at 1 mL/min isopropanol, at all pressures > 1 MPa (10 bar, 147 psi) Low delay volume configuration: < 5% amplitude (typically < 2 %) 

1260 Infinity Binary Pump VL:
< 2 % amplitude (typically < 1.3 %) or < 0.3 MPa (3 bar), whatever is greater, at 1 mL/min isopropanol, at all pressures > 1 MPa (10 bar, 147 psi)
Compressibility compensation 1260 Infinity Binary Pump:
Pre-defined, based on mobile phase compressibility

1260 Infinity Binary Pump VL:
User selectable, based on mobile phase compressibility
Recommended pH range 1.0 - 12.5, solvents with pH < 2.3 should not contain acids which attack stainless steel
Gradient formation High-pressure binary mixing
Delay volume 1260 Infinity Binary Pump: 
Standard delay volume configuration: 600 - 800 μL (includes 400 μL mixer), dependent on back pressure; measured with water at 1 mL/min (water/caffeine tracer) 
Low delay volume configuration: 120 µL

1260 Infinity Binary Pump VL:
600 - 900 µL (includes 400 μL mixer), dependent on back pressure
Composition range Settable range: 0 - 100 %
Recommended range: 1 - 99 % or 5 µL/min per channel, whatever is greater
Composition precision < 0.15 % RSD or < 0.04 min SD, whatever is greater, at 0.2 and 1 mL/min; based on retention time at constant room temperature
Composition accuracy 1260 Infinity Binary Pump:
± 0.35 % absolute, at 2 mL/min, at 10MPa (100 bar), (water/caffeine tracer)

1260 Infinity Binary Pump VL:
< 0.5 % absolute
Control Agilent control software (e.g. ChemStation, EZChrom, OL, MassHunter)
Local control Agilent Instant Pilot
Communications Controller-area network (CAN), RS-232C, APG Remote: ready, start, stop and shut-down signals, LAN optional
Safety and maintenance Extensive diagnostics, error detection and display through Agilent LabAdvisor, leak detection, safe leak handling, leak output signal for shutdown of the pumping system. Low voltage in major maintenance areas.
GLP features Early maintenance feedback (EMF) for continuous tracking of instrument usage in terms of seal wear and volume of pumped mobile phase with pre-defined and user settable limits and feedback messages. Electronic records of maintenance and errors
Housing All materials are recyclable