Tricyclic Antidepressants in Plasma / Serum
Tricyclic antidepressants (TCA) are a group of psychoactive drugs which are mainly used for the therapy of endogene depressions, anxiety and in the pain management.
Manual Sample Preparation.
The ClinMass® Add-on Set for TCAs (order no.MS9100) contains all analyte specific components required for the quantification of 13 TCAs + 2 neuroleptics. The ClinMass® TDM Platform (order no. MS9000) contains the components needed for sample preparation and LC-MS/MS analysis. It can be used with all ClinMass® Add-on Sets of the TDM Kit System (BZP, TCA, …).
On-line SPE.
The ClinMass® Add-on Set for TCAs (order no. MS9150) contains all analyte specific components required for the quantification of 13 TCAs and 2 atypical neuroleptics. The ClinMass® TDM Platform (order no. MS9050) contains the components needed for on-line SPE LCMS/ MS analysis. It can be used with all ClinMass® Add-on Sets of the “TDM Kit System, on-line” (BZP, TCA, …). The analytical column is suitable for the whole analyte panel (153 compounds).
Analytical Parameters:
| Amitryptyline | Imipramine | Normaprotiline |
| Clomipramine | Maprotiline | Nortrimipramine |
| Clozapine | Norclomiprapine | Nortriptyline |
| Desipramine | Norclozapine | Protriptyline |
| Doxepin | Nordoxepin | Trimipramine |
We have available an user manual for this application. You can request sending an email to clinica@ingenieria-analitica.com
|
Order No. |
Description |
Quantity |
|
MS9000 |
ClinMass® TDM Platform, on-line for 400 assays |
1 pce. |
|
Kit Components (order no. MS9000): |
||
|
MS9005 |
Autosampler Washing Solution |
1000 ml |
|
MS9007 |
Mobile Phase A |
2 x MS9007 (2 x 1000 ml) |
|
MS9008 |
Mobile Phase B |
1000 ml |
|
MS9020 |
Sample preparation vials |
4 x 100 vials |
|
MS9021 |
Precipitant P |
2 x 25 ml |
|
Start Accessories: |
||
|
MS9030 |
Analytical Column with test chromatogram |
1 pce. |
|
MS9032 |
Prefilter |
1 pce. |
|
Accessories: |
||
|
MS9022 |
Diluting Solution D |
50 ml |
|
MS9150 |
ClinMass® Add-on Set, for Tricyclic Antidepressants in Serum / Plasma for 200 assays |
1 pce. |
|
Kit Components (order no. MS9100): |
||
|
MS9112 |
Internal Standard IS, lyophil. |
5 x 5 ml |
|
MS9113 |
Serum Calibrator Set, lyophil. (Level 0 – 3) |
4 x 1 x 1 ml |
|
Manual |
1 pce. |
|
|
Start Accessories: |
||
|
MS9114 |
Optimisation Mix, lyophil. |
3x 1 x 2 ml |
|
ClinChek® Controls: |
||
|
MS9182 |
Serum Control, lyophil., Level I, II |
2 x 5 x 1 ml |
