Neuroleptics in Plasma / Serum

Neuroleptics belong to the class of psychoactive drugs and are administered in the therapy of psychoses, in particular in the symptomatic treatment of schizophrenia.

Manual Sample Preparation:

The ClinMass® Add-On Set for Neuroleptics (order no. MS9300) contains all analyte-specific components for the determination of 28 different neuroleptics. The ClinMass® TDM Platform (order no. MS9000) contains the components needed for sample preparation and LC-MS/MS analysis. It can be used with all ClinMass® Add-on Sets of the TDM Kit System (BZP, TCA, …). The analytical column is suitable for the whole analyte panel (156 compounds).

On-line SPE:

The ClinMass® Add-On Set, for Neuroleptics, on-line, (order no. MS9350) contains all analyte specific components for the determination of 28 different neuroleptics. The analysis is performed by HPLC with tandem mass spectrometry (LC-MS/MS). The ClinMass® TDM Platform (order no. MS9050) contains the components needed for sample preparation and LC-MS/MS analysis. It can be used with all ClinMass® Add-on Sets of the TDM Kit System (BZP, TCA, …). The analytical column is suitable for the whole analyte panel (153 compounds).

 

Analytical Parameters: 

Sulpiridine                                    Norclozapine Ziprasidone Dehydro-Aripiprazole
Amisulpride Olanzepine Levomepromazine Chlorprothixene
Paliperiodone Norquetiapine Perazine Flupentixol
Desmethylolanzapine Prothipendyl Zuclopenthixol Thioridazine
Pimpamperone Haloperidol Chlorpromazine Aripiprazole
Melperone Quetiapine Sertindole Zotepine         
Risperidone Promethazine Fluphenazine  

 

We have available an user manual for this application. You can request sending an email to clinica@ingenieria-analitica.com 

Order No.

Description

Quantity

MS9000

ClinMass® TDM Platform for 400 assays

1 pce.

Kit Components (order no. MS9000): 

MS9005

Autosampler Washing Solution

1000 ml

MS9007

Mobile Phase A

2 x MS9007 (2x 1000 ml)

MS9008

Mobile Phase B

1000 ml

MS9020

Sample Preparation Vials

4 x MS9020 (4 x 100 pcs.)

MS9021

Precipitant P

2 x MS9021 (2 x 25 ml)

Start Accessories: 

MS9030

Analytical Column with test chromatogram

1 pce.

MS9032

Prefilter

1 pce.

Accessories: 

MS9022

Diluting Solution D

50 ml

MS9300

ClinMass® Add-on Set for Neuroleptics in Serum / Plasma for 200 assays

1 pce.

Kit Components (order no. MS9300):

MS9312

Internal Standard IS, lyophil.

5 x 5 ml

MS9313

Serum Calibrator Set, lyophil. (Level 0 – 3)

4 x 1 x 1 ml

 

Manual

 

Start Accessories: 

MS9314

Optimisation Mix, lyophil.

2 x 1 x 2 ml

ClinChek® Controls: 

MS9382

Serum Control, lyophil., Level I, II

2 x 5 x 1 ml