Methylmalonic Acid in Plasma / Serum / Urine, Avanced

Methylmalonic acid (MMA) serves for the assessment of the vitamin B12 status. Vitamin B12 deficiency leads to an increased MMA concentration in serum, plasma and urine.

The RECIPE ClinMass® Complete Kit provides a fast MMA analysis featuring short sample preparation with only one pipetting step (serum, plasma) or direct injection of samples after dilution and addition of IS (urine). The subsequent LC-MS/MS analysis is performed within a 2 min injection interval only while the isobar component succinic acid, which may interfere with MMA, is reliably separated. The method is fully validated using only one (serum) calibration and control set for all three sample matrices (ClinCal® 4-Level Calibrator Set and ClinChek® Controls).

We have available an user manual for this application. You can request sending an email to clinica@ingenieria-analitica.com 

Order No. Description Quantity
MS5100 ClinMass® Complete Kit, advanced, 1 pce.
  for Methylmalonic Acid in Serum / Plasma / Urine  
  for 300 assays  
  Contents:  
  Autosampler Washing Solution 1 x MS5005
  Mobile Phase A 1 x MS5208
  Mobile Phase B 1 x MS5209
  Precipitant P with Internal Standard 3 x MS5112
  Serum Calibrator Set, lyophil. (Level 0 – 3) 1 x MS5013
  Sample Preparation Vials 3 x MS5020
  Manual  
  Separately available components:  
MS5005 Autosampler Washing Solution 1000 ml
MS5208 Mobile Phase A 1000 ml
MS5209 Mobile Phase B 330 ml
MS5112 Precipitant P with Internal Standard 40 ml
MS5013 Serum Calibrator Set, lyophil. (Level 0 – 3) 4 x 1 x 2 ml
MS5114 Optimisation Mix 2 ml
MS5020 Sample Preparation Vials 100 pcs.
MS5021 Diluting Solution D for Urine 50 ml
  Start Accessory:  
MS5130 Analytical Column with test chromatogram 1 pce.
  ClinChek® Controls:  
MS5082 Serum Control, lyophil., 2 x 5 x 2 ml
  Level I, II