Hemoglobin Variants and Beta-Thalassemia Screening

Defects in genes, which are responsible for the synthesis of the hemoglobin molecule, result in a group of hereditary diseases termed as ”hemoglobinopathies”. Depending on the molecular defect, hemoglobinopathies may be classified in ”structural hemoglobin variants” and in ”thalassemias”.

This test kit allows for a reliable separation and identification of the common and clinically significant hemoglobin variants. For beta-thalassemia screening the kit ensures an exact quantification of HbF and HbA2. A ready-to-use test solution (containing HbA1c, HbF, HbA0, HbE, HbA2, HbD, HbS, HbC), a hemolysate calibrator (containing HbF, HbA2) as well as three hemolysate controls are available for quality assurance.

Order No.

Description

Quantity

13100

ClinRep® Complete Kit for Hemoglobin Variants and ß-Thalassemia Screening

1 pce.

in Whole Blood for 500 assays

   

Components of the Complete Kit (order no. 13100):

13101

ClinRep® Reagent Kit

1 pce.

13113

Hemolysate Calibrator HbF/A2, ready for use

5 x 3 ml

13130

Analytical Column with test chromatogram

pce.

 

Manual

1 pce.

 

Quick Reference

1 pce.

Components of the Reagent Kit (order no. 13101):

13107

Buffer 1

2500 ml

13108

Buffer 2

2500 ml

13109

Washing Solution W

2000 ml

13121

Hemolysis Reagent H

500 ml

Optional Components:

13114

Test Solution (HbA1c/F/A/E/A2/D/S/C), ready for use

5 x 3 ml

Accessories:

11024

Sample vials 1.5 ml without cap

1000 pcs.

FK5810

PEEK tubing (connection of prefilter and column)

1 pce.

FK5820

Stainless steel prefilter holder

1 pce.

FK5821

Replacement filter for stainless steel prefilter holder

10 pcs.

ClinChek® Controls:

13182

Hemolysate Control HbF/A2, Level I, II, ready for use

2 x 5 x 3 ml

13183

Hemolysate Control HbF/A2/S, Level I, ready for use

5 x 3 ml