Free Metanephrines

Plasma free metanephrines (PFM) are the most specific parameters for the diagnosis of extraadrenal chromaffin tumors. The measurement of PFMs (metanephrine (M), normetanephrine (NM) and 3-methoxytyramine (MT)) is challenging because of their polar nature, their low molecular weight and their low physiological concentration in human plasma.

Manual Sample Preparation.

This ClinMass® Complete Kit represents a reliable and standardised method for the determination of PFM. In contrast to most of the LC-MS/MS methods established in clinical routine analysis, this method does not require dilution or evaporation steps. The measurement of highly concentrated samples is guaranteed. Alternatively to this method with manual sample preparation for standard LC-MS/MS systems, RECIPE offers an LC-MS/MS Complete Kit with on-line SPE analysis.

On-line Analysis.

Most LC-MS/MS methods used in clinical routine analysis involve time- and labour-consuming manual sample preparation for solid phase extraction (SPE). In contrast to this the RECIPE ClinMass® Complete Kit provides a simple sample pretreatment with one-step protein precipitation and subsequent on-line SPE.

We have available an user manual for this application. You can request sending an email to clinica@ingenieria-analitica.com 

Order No.

Description

Quantity

MS11000

ClinMass® Complete Kit for Free Metanephrines in Plasma – on-line Analysis

for 200 assays

1 pce.

Kit Components (order no. MS11000):

MS11005

Autosampler Washing Solution

1000 ml

MS11007

Mobile Phase A

250 ml

MS11008

Mobile Phase B

2 x MS11008 (2 x 1000 ml)

MS11009

SPE-Buffer Load L

2 x MS11009 (2 x 1000 ml)

MS11010

SPE-Buffer Wash W

1000 ml

MS11012

Precipitant P with Internal Standard

30 ml

MS11013

Serum Calibrator Set, lyophil. (Level 0 – 4)

5 x 1 x 3 ml

MS11014

Optimisation Mix

2 ml

MS11020

Sample Pretreatment Vials

2 x MS11020 (2 x 100 pcs.)

 

Manual

1 pce.

Start Accessories:

MS11030

Analytical Column with test chromatogram

1 pce.

MS11031

SPE-Column

1 pce.

ClinChek® Controls:

MS11080

Serum Control, lyophil., Level I

10 x 3 ml

MS11081

Serum Control, lyophil., Level II

10 x 3 ml

MS11082

Serum Control, lyophil., Level III

10 x 3 ml

MS11083

Serum Control, lyophil., Level I, II, III

3 x 3 x 3 ml