Benzodiazepines in Plasma / Serum

Benzodiazepines (BZP) are a group of psychoactive drugs with a broad range of therapeutic effects. They belong to the most frequently prescribed drugs all over the world.

Manual Sample Preparation.

The ClinMass® Add-on Set for Benzodiazepines (order no. MS9500) contains all analyte specific components required for the quantification of 36 different drugs and metabolites. The ClinMass® TDM Platform (order no. MS9000) contains the components needed for sample preparation and LC-MS/MS analysis. It can be used with all ClinMass® Add-on Sets of the TDM Kit System (BZP, TCA, …). The analytical column is suitable for the whole analyte panel (156 compounds).

On-line SPE

The ClinMass® Add-on Set for Benzodiazepines (order no. MS9550) contains all analyte specific components required for the quantification of 35 different drugs and metabolites. The ClinMass® TDM Platform (order no. MS9050) contains the components needed for on-line SPE LCMS/MS analysis. It can be used with all ClinMass® Add-on Sets of the “TDM Kit System, on-line”. The analytical column is suitable for the whole analyte panel (153 compounds).

Analytical Parameters: 

7Aminotritazepam Zalepion Norclobazam Desalkylflurazeram Trazadone
7aminociotrazepam  OH-Triazolam Lorazepam Flunitrazepam Flurazepam
3Hydroxibromazepam OH-Alprazolam Clonazepam Temazepam Midazolam
7Aminoflunitrazepam Desmethylunitrazepam Zolpidem Chlordiazepoxide Brotizolam Diazepam
Bromazepam Oxazepam Alprazolam Nordiazepam Tetrazepam
Demoxepam Nitrazepam OH-Midazolam Clobazam Prazepam
Zopiclon Estarblam Trizaolam    Lometazepan Medazepam

 

We have available an user manual for this application. You can request sending an email to clinica@ingenieria-analitica.com 

 

 

Order No.

Description

Quantity

MS9000

ClinMass® TDM Platform,  for 400 assays

1 pce.

Kit Components (order no. MS9000):

MS9005

Autosampler Washing Solution

1000 ml

MS9007

Mobile Phase A

2 x MS9007 (2 x 1000 ml)

MS9008

Mobile Phase B

1000 ml

MS9020

Sample preparation vials 

4 x MS9020

MS9021

Precipitant P

2 x MS9021

Start Accessories:

MS9030

Analytical Column with test chromatogram

1 pce.

MS9032

Prefilter

1 pce.

Accessories:

MS9022

Diluting Solution D

50 ml

MS9500

ClinMass® Add-on Set, for Benzodiazepines in Serum / Plasma for 200 assays

1 pce.

Kit Components (order no. MS9500):

MS9512

Internal Standard IS, lyophil.

5 ml

MS6013

Serum Calibrator Set, lyophil. (Level 0 – 3)

4 x 1 x 1 ml

 

Manual

1 pce.

Start Accessories:

MS6015 

Optimisation Mix 1 – 5, lyophil.

2 ml 

ClinChek® Controls:

MS6082

Serum Control, lyophil., Level I, II

2 x 5 x 1 ml