Antiepileptic Drugs in Plasma / Serum
Antiepileptic drugs (AED) are used for the treatment of epilepsy, a chronic neurological disorder, which is characterised by recurrent epileptic seizures.
Manual Sample Preparation
The ClinMass® Add-on Set for Antiepileptic Drugs (order no. MS9200) contains all analyte specific components required for the quantification of 27 different AEDs and metabolites. The ClinMass® TDM Platform (order no. MS9000) contains the components needed for sample preparation and LC-MS/MS analysis. It can be used with all ClinMass® Add-on Sets of the TDM Kit System. The analytical column is suitable for the whole analyte panel (156 compounds).
On-line SPE
The ClinMass® Add-on Set for Antiepileptic Drugs (order no. MS9250) contains all analyte specific components required for the quantification of 26 different AEDs and metabolites. The ClinMass® TDM Platform (order no. MS9050) contains the components needed for on-line SPE LCMS/MS analysis. It can be used with all ClinMass® Add-on Sets of the “TDM Kit System, on-line” (BZP, TCA, …). The analytical column is suitable for the whole analyte panel (153 compounds).
Analytical Parameters:
| 10-OH Cabamazepine | Levetiracetam | Retigabine |
| Carbamazepine | N-Desmethylmethsuximide | Rufinamide |
| Carbamazepine-diol | Oxcarbazepine | Stiripentol |
| Carbamazepine-epoxide | PEMA | Sulthiame |
| Felbamate | Perampanel | Tiagabine |
| Ethosuximide | Phenorbarbital | Topiramate |
| Gabapentine | Phenytoin | Valproic Acid |
| Lacosamide | Pregabaline | Zonisamide |
| Lamotrigine | Primidone |
We have available an user manual for this application. You can request sending an email to clinica@ingenieria-analitica.com
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Order No. |
Description |
Quantity |
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MS9000 |
ClinMass® TDM Platform for 400 assays |
1 pce. |
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Kit Components (order no. MS9000): |
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MS9005 |
Autosampler Washing Solution |
1000 ml |
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MS9007 |
Mobile Phase A |
2 x MS9007 (2 x 1000 ml) |
|
MS9008 |
Mobile Phase B |
1000 ml |
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MS9020 |
Sample Preparation Vials |
4 x MS9020 (4 x 100 pcs.) |
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MS9021 |
Precipitant P |
2 x MS9021 (2 x 25 ml) |
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Start Accessories: |
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MS9030 |
Analytical Column with test chromatogram |
1 pce. |
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MS9032 |
Prefilter |
1 pce. |
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Accessories: |
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MS9022 |
Diluting Solution D |
50 ml |
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MS9200 |
ClinMass® Add-on Set for Antiepileptic Drugs in Serum / Plasma for 200 assays |
1 pce. |
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Kit Components (order no. MS9200): |
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MS9212 |
Internal Standard IS, lyophil. |
5 x 5 ml |
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MS9213 |
Serum Calibrator Set, lyophil. (Level 0 – 3) |
4 x 1 x 1 ml |
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Manual |
1 pce. |
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Start Accessories: |
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MS9214 |
Optimisation Mix, lyophil. |
5 x 2 ml |
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ClinChek® Controls: |
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MS9282 |
Serum Control, lyophil., Level I, II |
2 x 5 x 1 ml |
