Antidepressant in Plasma / Serum

In addition to the classical TCAs a variety of next generation antidepressants (ADP) is available for the treatment of depressions, such as selective serotonin and norepinephrine reuptake inhibitors (SSRIs, SNRIs, NRIs) and TCAs.

Manual Sample Preparation

The ClinMass® Add-on Set for Antidepressants (order no. MS9400) contains all analyte specific components required for the quantification of 36 different ADPs and metabolites. The ClinMass® TDM Platform (order no. MS9000) contains the components needed for sample preparation and LC-MS/MS analysis. It can be used with all ClinMass® Add-on Sets of the TDM Kit System (BZP, TCA, …). The analytical column is suitable for the whole analyte panel (156 compounds).

On-line SPE

The ClinMass® Add-on Set for Antidepressants (order no. MS9450) contains all analyte specific components required for the quantification of 37 different ADPs and metabolites. The ClinMass® TDM Platform (order no. MS9050) contains the components needed for on-line SPE LCMS/MS analysis. It can be used with all ClinMass® Add-on Sets of the “TDM Kit System, on-line”. The analytical column is suitable for the whole analyte panel (153 compounds).

Analytical Parameters: 

Amityptiline Norclozapine
Clomipramine Nordoxepin
Clozapine Normaprotiline
Desipramine Nortrimipramine
Doxepin Nortyptyline
Imipramine Protriptyline
Maprotiline Trimipramine
Norclomipramine  

 

We have available an user manual for this application. You can request sending an email to clinica@ingenieria-analitica.com 

Order No.

Description

Quantity

MS9000

ClinMass® TDM Platform for 400 assays

1 pce.

Kit Components (order no. MS9000):

MS9005

Autosampler Washing Solution

1000 ml

MS9007

Mobile Phase A

2 x MS9007 (2 x 1000 ml)

MS9008

Mobile Phase B

1000 ml

MS9020

Sample Preparation Vials

4 x MS9020 (4 x 100 pcs.)

MS9021

Precipitant P

2 x MS9021 (2 x 25 ml)

Start Accessories:

MS9030

Analytical Column with test chromatogram

1 pce.

MS9032

Prefilter

1 pce.

Accessories:

MS9022

Diluting Solution D

50 ml

MS9400

ClinMass® Add-on Set for Antidepressants in Serum / Plasma for 200 assays

1 pce.

Kit Components (order no. MS9400):

MS9412

Internal Standard IS, lyophil.

5 x 5 ml

MS9413

Serum Calibrator Set, lyophil. (Level 0 – 3)

4 x 1 x 1 ml

 

Manual

1 pce.

Start Accessories:

MS9414

Optimisation Mix, lyophil.

2 x 2 ml

ClinChek® Controls:

MS9482

Serum Control, lyophil., Level I, II

2 x 5 x 1 ml