ALEXYS Azithromycin Analyzer

An ALEXYS method has been developed for the analysis of Azithromycin following the official USP method. The USP method for Azi uses two flow cells in series, cell 1 for screening and cell 2 for detection of the analytes. The first flow cell is a Reactor cell, the second is the SenCell. Under the specified LC conditions all USP criteria are met. Chromatogram: a mixture of several macrolides was analysed to illustrate the chromatographic performance of the method. All components are separated with at least a resolution of 2.5.

  • Excellent reproducibility and linearity
  • In compliance with USP requirements
  • Total analysis time <14 min

Configuración del sistema:

For the analysis of Azythromycin we selected the SenCell. This cell not only has an excellent reproducibility but also the best possible detection sensitivity. A Reactor was used as pre-oxidation screening cell to meet USP requirements. The ALG is a USP L49 type of column.

The ALEXYS system comprises the following parts:

  • AS 110 autosampler, cool
  • LC 110S HPLC pump
  • OR 110 organiser rack
  • Clarity data acquisition software
  • DECADE II electrochemical detector, DCC
  • SenCell with GC WE, sb REF
  • Flexcell with GC WE and HyREF

 Part Number 

 Description

180.0086C

 ALEXYS Azithromycin Analyzer, USP