1290 Infinity Quaternary LC System

The Agilent 1290 Infinity Quaternary LC System provides highest accuracy and precision combined with the flexibility of a quaternary system. The 1290 power range and the Intelligent System Emulation Technology (ISET) give you the possibility to develop run high-end UHPLC methods and still run your established legacy HPLC methods on the same system. TheBlendAssist feature in the software offers a comfortable, precise and accurate way of buffer/additive blending, saving time and money in your daily lab routine. Equipped with the 1290 Infinity Diode Array Detector and the next-generation 1290 Infinity Autosampler you will achieve highest sensitivity at lowest carry over and highest precision. Lab Advisor software helps manage your lab for best chromatographic quality.

  • Intelligent System Emulation Technology (ISET) provides seamless transfer of methods between LCs, regardless of the brand, delivering unchanged retention time and peak resolution.

  • Binary-pump like performance in terms of accuracy and precision

  • Extended power range that combines ultra high pressure up to 1200 bar and high analytical flow rates up to 5 mL/min for maximum chromatographic performance

  • Optical design in 1290 Infinity Diode Array Detector – including Agilent Max-Light cartridge flow cell – offers a new level of UV-sensitivity and baseline robustness, including fast spectral acquisition at data rates up to 160 Hz

  • Ultra sensitivity is achieved through revolutionary Agilent Max-Light cartridge cell with 60 mm optical path length (typically noise: < ± 0.5 µAU/cm) providing more than 10 times higher sensitivity than the 1200 Series DAD and VWD detectors

  • Next generation flow-through design of the 1290 Infinity Autosampler achieves lowest carry over

  • 1290 Infinity Flexible Cube combined with the 1290 Infinity Autosampler to facilitate automatic backflushing of needle seat for a new benchmark in lowest carry over (typically

  • 1290 Infinity LC Injector HTC/HTS is designed specifically to meet the throughput and reliability demands of critical LC/MS applications, offering lowest carryover with dynamic load and wash (DLW) principle

  • Pull-out valve drive and user-exchangeable valve heads in the 1290 Infinity Thermostatted Column Compartment boosts usability and paves the way for ultra high-throughput, multi-method and automated method development solutions

  • ZORBAX Rapid Resolution High Definition (1.8 µm) LC columns – facilitate easy, fast and secure method transfer from HPLC to UHPLC through identical column chemistries

  • Lab Advisor software– with intuitive diagnostic and monitor capabilities and alert functions to notify you of problems – helps you manage your lab for best chromatographic quality.

  • 1290 Infinity LC Injector HTC/HTS  is designed specifically to meet the throughput and reliability demands of critical LC/MS applications, offering lowest carryover with dynamic load and wash (DLW) principle

 

Specifications Agilent 1290 Infinity Quaternary Pump (G4204A)

Hydraulic system

Dual pistons in series pump with proprietary servo-controlled variable stroke design and smooth motion control for active damping.

Pump resolution step size

300pl step size

Settable flow range

0.001 – 5 mL/min, in 0.001 mL/min increments (- executed in 300 pL/step increments)

Flow precision

<=0.07 % RSD, or 0.01 min SD, whatever is greater (0.2 - 5.0 mL/min); based on retention time at constant room temperature

Flow accuracy

±1% or ±10 μL/min, whatever is greater;pumping degassed H2O at 10 MPa (100 bar).

Maximum operating pressure

Operating range up to 120 MPa (1200 bar) up to 2 mL/min, ramping down to 80 MPa (800 bar) up to 5 mL/min.

Pressure pulsation

< 1 % amplitude or < 0.5 MPa (5 bar) whatever is greater at 1 mL/min water.

Compressibility compensation

Automatic, pre-defined, based on mobile phase selection.

pH-range

1.0 – 12.5, solvents must be compatible with wetted material

Gradient formation

Low pressure quaternary mixing

Delay volume

Standard configuration: < 350 μL
With optional V380 Jet Weaver Mixer: < 500 μL

Composition range

Settable range: 0.0 – 100.0 %
Recommended range: 1.0 – 99.0 % or 5 µL/min per channel, whatever is greater.

Composition precision

< 0.15 % RSD, or 0.02 min SD whatever is greater (1 mL/min); based on retention time at constant room temperature

Composition accuracy

±0.4 % absolute (1 - 99 % B, 0.5 - 2.0 mL/min with water/caffeine tracer, 400bar)

Integrated degassing unit

Number of channels: 4 internal volume per channel: 1.5 mL materials in contact with solvent: TFE/PDD Copolymer, FEP, PEEK, PPS.

Materials in contact with solvent

TFE/PDD copolymer, FEP, PEEK, PPS, stainless steel, polyimide

Control

Agilent OpenLAB CDS ChemStation edition C.01.04 or above
Agilent OpenLAB CDS EZChrom edition A.04.04 or above
Agilent MassHunter B05.01 or above
Agilent Instrument Control Framework ICF A.01.05 or above

Local control

Agilent Instant Pilot (G4208A) (B.02.08 or above)

Communications

Controller-area network (CAN), RS232C, APG remote: ready, start, stop and shutdown signals, LAN

Safety and maintenance

Extensive diagnostics, error detection and display through Agilent LabAdvisor, leak detection, safe leak handling, leak output signal for shutdown of the pumping system. Low voltage in major maintenance areas.

GLP features

Early maintenance feedback (EMF) for continuous tracking of instrument usage in terms of seal wear and volume of pumped mobile phase with pre-defined and user settable limits and feedback messages. Electronic records of maintenance and errors.

 

All materials are recyclable.