1290 Infinity LC Injector HTC/HTS

High throughput with lowest carryover

The Agilent 1290 Infinity LC Injector HTC/HTS is designed specifically to meet the throughput and reliability demands of critical LC/MS applications. The device offers the lowest carryover available with the dynamic load and wash (DLW) principle and enables improved cycle times through the use of faster mechanisms. This highly versatile system is optimized for high throughput injections and perfectly complements the market-leading high speed, resolution and sensitivity of the Agilent 1290 Infinity LC system. Temperature controlled storage conserves sample integrity and a variety of software options are available for different applications.

  • Near zero carryover provided by the innovative dynamic load and wash principle (DLW).

  • Improved cycle time created by faster robotics and washing mechanisms.

  • Proprietary 1200 bar valve for more robust UHPLC analysis — available exclusively from Agilent.

  • High sample capacity for up to 24 cooled well plates.

  • High level of compatibility with easy control and data handling through Mass Hunter, OpenLab Chemstation and OpenLab EZChrom software.

  • Temperature-controlled sample storage that keeps a variety of samples cool and stable preventing degradation.

System Type

Syringe size

100 µL

Loop sizes for DLW and maximum pressure rating

2 µL (standard) 1200 bar max., 
5 µL, 10 µL, 20 µL 1000 bar max., 
50 µL and 100 µL 600 bar max.

LC injector

1 electrically actuated fast switching 6-port valve from Rheodyne (1200 bar)

Injection volumes

Up to 100 µL with standard setup, up to 5 ml with additional hardware

HTC sample capacity

Up to 24 shallow well-plates (96 or 384)
Up to 12 deep well-plates (96 or 384), or 648 2-mL vials
Up to 12 shallow well-plates (96 or 384), thermostatted
Up to 6 deep well-plates (96 or 384), or 324 2-mL vials, thermostatted

Injection precision

<0. 5% with 100 ul syringe and 2 ul loop, overfill 7ul

HTS sample capacity

Up to 24 shallow well-plates (96 or 384)
Up to 18 deep well-plates (96 or 384), or 972 2-mL vials
Up to 12 deep well-plates (96 or 384), or 648 2-mL vials, thermostatted

Needle, syringe valve cleaning

Dynamic load and wash (DLW) principle: two different solvents

Carryover

Typically < 0.004% with DLW Method: Chlorohexidine, 0.6 mg/L dissolved in H2O : ACN = 90 : 10, 0.1% TFA
Blank Solution: H2O : ACN = 90 : 10, 0.1% TFA

Local control

Handheld control panel with 4 function keys, graphical LCD display

Electronic control

2 RS232C ports 
3 TTL inputs 
1 opto-coupler input 
2 relay outputs

Thermal control

4-40C (settable)

System Type

XYZ Robot With Syringe-Only Concept, No Tubing In Sample Path

Syringe size

100 µL

Loop sizes for DLW and maximum pressure rating

2 µL (standard) 1200 bar max., 
5 µL, 10 µL, 20 µL 1000 bar max., 
50 µL and 100 µL 600 bar max.

LC injector

1 electrically actuated fast switching 6-port valve from Rheodyne (1200 bar)

Injection volumes

Up to 100 µL with standard setup, up to 5 ml with additional hardware

HTC sample capacity

Up to 24 shallow well-plates (96 or 384)
Up to 12 deep well-plates (96 or 384), or 648 2-mL vials
Up to 12 shallow well-plates (96 or 384), thermostatted
Up to 6 deep well-plates (96 or 384), or 324 2-mL vials, thermostatted

Injection precision

<0. 5% with 100 ul syringe and 2 ul loop, overfill 7ul

HTS sample capacity

Up to 24 shallow well-plates (96 or 384)
Up to 18 deep well-plates (96 or 384), or 972 2-mL vials
Up to 12 deep well-plates (96 or 384), or 648 2-mL vials, thermostatted