1290 Infinity Binary LC System
The Agilent 1290 Infinity Binary LC is not only the most powerful but also the most adaptive UHPLC system available. No matter what your laboratory requires, the 1290 Infinity Binary LC can handle the widest range of applications; UHPLC methods, legacy HPLC methods, HPLC-to-UHPLC method transfer, method development, multi-compound screening, LC/MS coupling, and many more.
- Most adaptive – emulates other HPLC and UPLC systems, connects to all Agilent and many non-Agilent software
- Highest performance & flexibility – by any measure
- HPLC-like service costs – UHPLC productivity
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Intelligent System Emulation Technology (ISET) provides seamless transfer of methods between LCs, regardless of the brand, delivering unchanged retention time and peak resolution.
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Infinite power range that combines ultra high pressure up to 1200 bar and high flow rates up to 5 mL/min for maximum chromatographic performance, compatibility, flexibility and investment protection.
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The 1290 Infinity binary pump combines active damping with lowest delay volume down to <10 µL
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Optical design in 1290 Diode Arrray Detector – including Agilent Max-Light cartridge flow cell – offers a new level of UV-sensitivity and baseline robustness, including fast spectral acquisition at data rates up to 160 Hz.
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Ultra sensitivity is achieved through revolutionary Agilent Max-Light cartridge cell with 60 mm optical path length (typical noise: < ± 0.6 µAU/cm) providing more than 10 times higher sensitivity than the 1200 Series DAD and VWD.
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Expand your UV-detection capabilities with the 30x wider linear UV-range offered by the new HDR-DAD solution - making it ideal for analysis of mixtures with widely different concentration levels.
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Next generation flow-through design of the 1290 Infinity Autosampler achieves lowest carry over (<0.004%)
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1290 Infinity Flexible Cube combined with the 1290 Infinity Autosampler to facilitate automatic backflushing of needle seat for a new benchmark in lowest carry over (typically <0.0010%, <10 ppm)
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1290 Infinity LC injector HTC/HTS is designed specifically to meet the throughput and reliability demands of critical LC/MS applications, offering lowest carryover with dynamic load and wash (DLW) principle.
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Pull-out valve drive and user-exchangeable valve heads in the 1290 Infinity Thermostatted Column Compartment boosts usability and paves the way for ultra high-throughput, multi-method and automated method development solutions.
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ZORBAX Rapid Resolution High Definition (1.8 µm) LC columns facilitate easy, fast and secure method transfer from HPLC to UHPLC through identical column chemistries.
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Lab Advisor Software– with intuitive diagnostic and monitor capabilities and alert functions to notify you of problems – helps you manage your lab for best chromatographic quality
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Hydraulic system |
Two dual pistons in series, pumps with proprietary servo-controlled variable stroke design and smooth motion control |
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Pump resolution step size |
300pl step size |
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Settable flow range |
0.001 – 5 mL/min, in 0.001 mL/min increments (- executed in 300 pL/step increments) |
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Flow precision |
<=0.07 % RSD or 0.005 min SD, whatever is greater (0.2 - 5.0 mL/min); based on retention time at constant room temperature |
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Flow accuracy |
±1% or 10 μL/min, whatever is greater; pumping degassed H2O at 10MPa (100 bar) |
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Pressure operating range |
1290 Infinity Binary Pump: Operating range up to 120 MPa (1200 bar) up to 2 mL/min, 80 MPa (800 bar) at 5 mL/min |
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Pressure pulsation |
< 1 % amplitude or < 0.5 MPa (5 bar), whatever is greater; at 1 mL/min water |
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Compressibility compensation |
Automatic, pre-defined, based on mobile phase selection |
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Recommended pH-range |
1.0 – 12.5, solvents with pH < 2.3 should not contain acid which attack stainless steel |
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Gradient formation |
High pressure binary mixing |
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Delay volume |
JetWeaver V35: < 45 μL |
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Composition range |
Settable range: 0 - 100 % |
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Composition precision |
< 0.15 % RSD or 0.01 min SD, whatever is greater (0.2 - 5 mL/min); based on retention time at constant room temperature |
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Composition accuracy |
±0.35 % absolute (5 - 95 %, 0.2 - 5.0 mL/min, water/caffeine tracer) |
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Solvent selection valve |
Default |
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Integrated degassing unit |
Number of channels: 2 Internal volume per channel: 1.5 mL Materials in contact with solvent: TFE/PDD Copolymer, FEP, PEEK, PPS |
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Control |
Agilent ChemStation for LC (B.04.02 or above) |
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Local control |
Agilent Instant Pilot (G4208A) (B.02.08 or above) |
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Communications |
Controller-area network (CAN), |
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Safety and maintenance |
Extensive diagnostics, error detection and display through Agilent LabAdvisor, leak detection, safe leak handling, leak output signal for shutdown of the pumping system. Low voltage in major maintenance areas |
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GLP features |
Early maintenance feedback (EMF) for continuous tracking of instrument usage in terms of seal wear and volume of pumped mobile phase with pre-defined and user settable limits and feedback messages. Electronic records of maintenance and errors |
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Housing |
All materials are recyclable |
