1260 Infinity Nanoflow Pump

The nanoflow pump features Electronic Flow Control (EFC) with active feedback and real-time flow adjustment. EFC is the gold standard for robust and reliable nanoflow performance. With accurate and precise flow and gradient performance, this pump gives consistent and reproducible retention times and excellent flow and gradient performance for stable ion generation which is essential for high sensitivity nanospray MS performance. A versatile pump system, the 1260 Infinity Nanoflow Pump can also be configured to deliver standard LC flow rates up to 2.5 ml/min.

  • Reliable and reproducible results - industry-leading flow sensor technology and the Electronic Flow Control (EFC) provide real-time adjustment of the flow rate throughout the analysis for consistent and reproducible retention times.

  • Two pumps in one – use nanoflow mode for optimized flow rates from 100 nl/min to 1 µL/min; use normal mode for flow rate up to 2.5 ml/min with easy hardware changes.

  • Fast changeover and rapid purging - micro vacuum degassing with very low internal volume per channel (1 ml) means you can quickly purge and change your mobile phase.

  • Convenience - a handheld controller makes it monitor the status of your run and couple it to mass spectrometry.

Agilent 1260 Infinity Nanoflow Pump

Hydraulic system

Two dual piston in series, with proprietary servo-controlled variable stroke drive, floating piston, active inlet valve, solvent selection valve and electronic flow control for flow rates from 0.1 to 1 µL/min

Settable column flow range

0.01 – 4 µL/min,
1 – 2500 µL/min (with the electronic flow control bypassed)

Recommended column flow range

0.1 – 1 µL/min
200 – 2500 µL/min (with the electronic flow sensor bypassed)

Optimum composition range

1 to 99% or 5 µL/min per channel (primary flow), whatever is greater

Composition precision

< 0.2 % SD, at 500 nl/min (default settings)
Minimum primary flow/pump channel is 5 µL/min

Delay volume

Typically 300 nL from the electronic flow control to the pump outlet for flow rates up to 4 µL/min. 
For flow rates up to 4 µL/min and electronic flow control active: primary flow path 180 - 480 µL; system pressure dependent (default settings; calculated volume)
Typically 180 to 480 µL (system pressure dependent) for flow rates up to 2.5 mL/min. (default settings; calculated volume)

Pressure range

20 to 400 bar (5880 psi) system pressure

Compressibility compensation

User-selectable, based on mobile phase compressibility

Recommended pH range

1.0 – 8.5, solvents with pH < 2.3 should not contain acids which attack stainless steel. Upper pH range is limited by fused silica capillaries.

Control and data evaluation

Agilent ChemStation for LC and Agilent MassHunter for LC/MS

Analog output

For pressure monitoring, 2 mV/bar, one output

Communications

Controller-area network (CAN), GPIB, RS-232C, APG Remote: ready, start, stop and shut-down signals, LAN optional